Lactobacillus paracasei, L. CASEI 431®
- a well-documented probiotic strain
The L. CASEI 431® probiotic strain may help support the immune system1, 2, 3, 4 and digestive health.5
Chr. Hansen Lactobacillus paracasei, L. CASEI 431®
The L. CASEI 431® probiotic strain was originally isolated from a healthy baby’s stool sample. L. CASEI 431® survives the journey through the acidic digestive system to the intestine where the bacteria may play a role in supporting health. It has been used in food and dietary supplements since 1995.
The L. CASEI 431® strain has been described in around 60 scientific publications, of which more than 20 are publications of human scientific studies. The reports associate the L. CASEI 431® probiotic strain with supporting immune health in adults1, 2, 3, 4 and digestive health in babies.5
Lactobacillus paracasei, L. CASEI 431® has been associated with several health benefits
Supporting immune health
Consuming L. CASEI 431® has been associated with a higher number of antibodies (natural proteins that recognize foreign substances, such as harmful bacteria, and bind to them) following an immune challenge,1, 3, 4 suggesting that L. CASEI 431® may help support the body’s immune system.
Supporting respiratory health
Taking the L. CASEI 431® probiotic strain has been associated with fewer instances of respiratory tract discomfort, fewer visits to health care professionals, and less use of some health care interventions.2
Supporting digestive health
In combination with the Bifidobacterium, BB-12® probiotic strain, supplementing babies with L. CASEI 431® has been associated with softer stools and more regular bowel movements.5
SafetyLactobacillus paracasei, L. CASEI 431® is safe for human consumption; it has been granted QPS (Qualified Presumption of Safety) status from EFSA in Europe.6 It has been tested in human scientific studies at levels of up to at least 50 billion CFU/day, alone and in combination with Bifidobacterium, BB-12®, with no safety issues.
L. CASEI 431® is a registered trademark of Chr. Hansen A/S.
The article is provided for informational purposes regarding probiotics and is not meant to suggest that any substance referenced in the article is intended to diagnose, cure, mitigate, treat, or prevent any disease.
At Chr. Hansen, our strains are backed by science. All of our probiotic strains are supported by clinical documentation. Learn more about the beneficial effects our strains have on different health areas.
1. Rizzardini G, et al. Br J Nutr. 2012;107(6):876-84. (PubMed)
2. Jespersen L, et al. Am J Clin Nutr. 2015;101(6):1188-96. (PubMed)
3. Trachootham, D. et al. Journal of Functional Foods. 2017;33, 1–10.
4. De Vrese, M. et al. European Journal of Nutrition. 2005;44(7), 406–413. (PubMed)
5. Vlieger AM, et al. Br J Nutr. 2009;102(6):869-75. (PubMed)
6. EFSA Panel on Biological Hazards (BIOHAZ). EFSA Journal. 2015;13:4331.